APC: Psychedelic Facilitated Psychotherapy for Addiction-Potential Mechanisms

Potential Mechanisms - Psychedelics for SUDs_Rieser_2021

Pdf Summary

Psychedelic-assisted therapy has shown promise in treating substance use disorders (SUD) by inducing neuroplasticity, altering brain network connectivity, and enhancing emotion processing. They may also modulate reward and stress processing, increase social connectedness, and elicit subjective experiences that enhance motivation for change. Combining psychedelics with psychotherapeutic approaches, such as cognitive-behavioral therapy, can optimize treatment outcomes. Resting-state functional magnetic resonance imaging (fMRI) can be used to measure brain connectivity as a predictive biomarker for treatment success. More research is needed to determine optimal doses and timing of interventions. Overall, psychedelic-assisted therapy has the potential to be an effective evidence-based treatment for SUD.

Keywords

Psychedelic-assisted therapy

substance use disorders

neuroplasticity

brain network connectivity

emotion processing

reward processing

stress processing

social connectedness

cognitive-behavioral therapy

treatment success

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