false
OasisLMS
zh-CN,en,fr,de,ja,es
Catalog
35th AM (2025) - Poster Session
Treatment outcomes of an integrated treatment mode ...
Treatment outcomes of an integrated treatment model for patients with co-occurring opioid use and schizophrenia...
Back to course
Pdf Summary
This study evaluates treatment outcomes of a specialized integrated program (TOAST) designed for patients with co-occurring opioid use disorder (OUD) and schizophrenia spectrum disorders, a population at elevated risk for relapse and morbidity. The program includes a psychiatrist and therapist delivering weekly in-person groups, medication management (MOUD and antipsychotics including long-acting injectables), and therapy incorporating motivational interviewing, coping, relapse prevention, and psychoeducation. Patients were monitored with random urine drug screens and encouraged to self-report substance use.<br /><br />The cohort consisted of 17 patients (mean age 41, predominantly male and White) diagnosed with both OUD and schizophrenia spectrum disorders. Key findings include moderate appointment adherence at 58.8%, with 47.1% remaining actively enrolled after follow-up. Medication adherence rates were high: MOUD adherence at 90.5% and antipsychotics at 96.9%, notable given typical adherence challenges in this population.<br /><br />Regarding substance use patterns, no significant changes in opioid relapse were observed before and after program enrollment, but a significant increase in non-opioid drug use was noted, possibly due to enhanced surveillance. Importantly, there was a significant reduction in emergency department (ED) visits, inpatient hospitalizations, and hospitalization length following program participation, indicating improved health resource utilization.<br /><br />Specifically, mean ED visits dropped from 3.47 to 1.29, hospitalizations from 1.94 to 0.65, and hospitalization length decreased from 19.18 to 7.88 days. These reductions are clinically significant given the typically high utilization of acute care services in this group.<br /><br />In conclusion, the TOAST integrated treatment model shows promise in improving medication adherence, engagement, and reducing acute healthcare utilization among patients with dual diagnoses of OUD and schizophrenia spectrum disorders. Future research should continue to explore strategies to address non-opioid substance use and further enhance retention.
Keywords
opioid use disorder
schizophrenia spectrum disorders
integrated treatment program
TOAST program
medication adherence
MOUD
antipsychotics
relapse prevention
emergency department visits
healthcare utilization
×