35th AM (2024) - Poster Session-Correlation Bet Adverse Childhood Experiences and SUDs in ALD final

Correlation Bet Adverse Childhood Experiences and SUDs in ALD final

Pdf Summary

The study investigates the relationship between Adverse Childhood Experiences (ACEs) and substance use disorders (SUDs) in patients with severe alcohol-associated liver disease (ALD). Conducted at the multidisciplinary ALD clinic, the research retrospectively analyzed data from 35 patients diagnosed with ALD, focusing on the correlation between ACE scores and SUDs, utilizing logistic regression models to account for variables such as sex and race.<br /><br />Key findings highlight significant associations between high ACE scores and increased risks of polysubstance use among ALD patients. Specifically, experiences of parental loss and living with an incarcerated individual showed strong correlations with co-occurring SUDs, with individuals being 21.41 and 20.87 times more likely, respectively, to have additional SUDs. Overall, each one-unit increase in ACE score elevated the odds of having a co-occurring SUD by a factor of 1.61, reinforcing the impact of childhood adversity on later substance use behaviors.<br /><br />The study suggests implementing ACE screenings in liver clinics to identify at-risk patients and develop specialized treatment plans, acknowledging childhood trauma's substantial role in the development of SUDs among individuals with ALD. However, with a small sample size of 35 patients, the study's conclusions are limited by wide confidence intervals and potential variables like genetic factors or socioeconomic status not fully accounted for, suggesting further research with larger sample sizes is necessary for validation and exploration of additional mechanisms.<br /><br />The research emphasizes the importance of addressing past childhood adversities to mitigate substance use complications in individuals suffering from alcohol-associated liver diseases, providing insights for more comprehensive clinical interventions and support strategies.

Keywords

Adverse Childhood Experiences

Substance Use Disorders

Alcohol-Associated Liver Disease

ACE scores

Polysubstance Use

Parental Loss

Incarceration

Childhood Trauma

Logistic Regression

Clinical Interventions

	The content on this site is intended solely to inform and educate medical professionals. This site shall not be used for medical advice and is not a substitute for the advice or treatment of a qualified medical professional.		400 Massasoit Avenue Suite 307 East Providence, RI 02914 cmecpd@aaap.org	About Advocacy Membership Fellowship Education and Resources Training Events