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Catalog
34th AM (2023) - Poster Session
Let’s SROM with it: Rotating Methadone to Buprenor ...
Let’s SROM with it: Rotating Methadone to Buprenorphine
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Pdf Summary
The study conducted by Tianna Costa, Ari Cuperfain, Maddy Hannah, and Nitin Chopra focuses on the role of slow-release oral morphine (SROM) in switching methadone to buprenorphine, particularly in Canada. Buprenorphine-naloxone (bup/nlx) is considered the preferred first-line treatment option, followed by methadone. However, SROM is an alternative option available in Canada. <br /><br />The use of SROM allows for the continuation of evidence-based opioid agonist therapy (OAT) and preserved tolerance during the transition from methadone to buprenorphine. It also helps manage withdrawal symptoms, cravings, and pain. <br /><br />The study provides three cases that demonstrate the utility of SROM in this transition. Patient A, a 31-year-old male with new-onset psychosis, tolerated the induction well. Patient B, a 34-year-old male with stimulant-induced psychosis, also had a successful transition. Patient C, a 62-year-old female with adherence issues to methadone and suicidal ideation, experienced precipitated withdrawal due to reduced renal function. However, the withdrawal was managed with continued doses of buprenorphine and PRN clonidine. <br /><br />The method of transitioning from methadone to buprenorphine using SROM involves gradually reducing the methadone dose, initiating SROM, and then transitioning to buprenorphine. The specific protocol for each patient is provided in Table 2 of the study.<br /><br />Overall, the study concludes that SROM can be a useful tool in facilitating the transition from methadone to buprenorphine. However, patient factors, including renal function, need to be considered when using this method.
Keywords
slow-release oral morphine
SROM
methadone to buprenorphine
Canada
opioid agonist therapy
withdrawal symptoms
cravings
pain management
transition protocol
renal function
The content on this site is intended solely to inform and educate medical professionals. This site shall not be used for medical advice and is not a substitute for the advice or treatment of a qualified medical professional.
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